Cargando…
Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons
Small-conductance Ca(2+)-activated K(+) channel activation is an emerging therapeutic approach for treatment of neurological diseases, including stroke, amyotrophic lateral sclerosis and schizophrenia. Our previous studies showed that activation of SK channels exerted neuroprotective effects through...
Autores principales: | Dolga, A M, de Andrade, A, Meissner, L, Knaus, H-G, Höllerhage, M, Christophersen, P, Zischka, H, Plesnila, N, Höglinger, G U, Culmsee, C |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040692/ https://www.ncbi.nlm.nih.gov/pubmed/24434522 http://dx.doi.org/10.1038/cddis.2013.530 |
Ejemplares similares
-
Protective Roles for Potassium SK/K(Ca)2 Channels in Microglia and Neurons
por: Dolga, Amalia M., et al.
Publicado: (2012) -
Mitochondrial damage by α-synuclein causes cell death in human dopaminergic neurons
por: Ganjam, Goutham K., et al.
Publicado: (2019) -
SK channel activation is neuroprotective in conditions of enhanced ER–mitochondrial coupling
por: Honrath, Birgit, et al.
Publicado: (2018) -
K(Ca)2 channels activation prevents [Ca(2+)](i) deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia
por: Dolga, A M, et al.
Publicado: (2011) -
Age-dependent neuroprotective effect of an SK3 channel agonist on excitotoxity to dopaminergic neurons in organotypic culture
por: Maldonado, Oscar, et al.
Publicado: (2020)