Plasmodium falciparum signal recognition particle components and anti-parasitic effect of ivermectin in blocking nucleo-cytoplasmic shuttling of SRP

Signal recognition particle (SRP) is a ubiquitous ribonucleoprotein complex that targets proteins to endoplasmic reticulum (ER) in eukaryotes. Here we report that Plasmodium falciparum SRP is composed of six polypeptides; SRP9, SRP14, SRP19, SRP54, SRP68 and SRP72 and a 303nt long SRP RNA. We genera...

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Detalles Bibliográficos
Autores principales: Panchal, M, Rawat, K, Kumar, G, Kibria, K M, Singh, S, Kalamuddin, Md, Mohmmed, A, Malhotra, P, Tuteja, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040695/
https://www.ncbi.nlm.nih.gov/pubmed/24434517
http://dx.doi.org/10.1038/cddis.2013.521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040695/
https://www.ncbi.nlm.nih.gov/pubmed/24434517
http://dx.doi.org/10.1038/cddis.2013.521

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