Cargando…

Plasmodium falciparum signal recognition particle components and anti-parasitic effect of ivermectin in blocking nucleo-cytoplasmic shuttling of SRP

Signal recognition particle (SRP) is a ubiquitous ribonucleoprotein complex that targets proteins to endoplasmic reticulum (ER) in eukaryotes. Here we report that Plasmodium falciparum SRP is composed of six polypeptides; SRP9, SRP14, SRP19, SRP54, SRP68 and SRP72 and a 303nt long SRP RNA. We genera...

Descripción completa

Detalles Bibliográficos
Autores principales:	Panchal, M, Rawat, K, Kumar, G, Kibria, K M, Singh, S, Kalamuddin, Md, Mohmmed, A, Malhotra, P, Tuteja, R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040695/ https://www.ncbi.nlm.nih.gov/pubmed/24434517 http://dx.doi.org/10.1038/cddis.2013.521

Ejemplares similares

Quinoline-triazole hybrids inhibit falcipain-2 and arrest the development of Plasmodium falciparum at the trophozoite stage
por: Singh, Anju, et al.
Publicado: (2019)

SUMOylation regulates nucleo-cytoplasmic shuttling of Elk-1
por: Salinas, Sara, et al.
Publicado: (2004)

Evidence for the Nucleo-Apical Shuttling of a Beta-Catenin Like Plasmodium falciparum Armadillo Repeat Containing Protein
por: Mitra, Pallabi, et al.
Publicado: (2016)

Interphase Nucleo-Cytoplasmic Shuttling and Localization of SIRT2 during Mitosis
por: North, Brian J., et al.
Publicado: (2007)

New insights into YAP/TAZ nucleo‐cytoplasmic shuttling: new cancer therapeutic opportunities?
por: Shreberk‐Shaked, Michal, et al.
Publicado: (2019)

Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function
por: Haward, Fiona, et al.
Publicado: (2021)

GNL3L Is a Nucleo-Cytoplasmic Shuttling Protein: Role in Cell Cycle Regulation
por: Thoompumkal, Indu Jose, et al.
Publicado: (2015)

And Yet It Moves: Oxidation of the Nuclear Autoantigen La/SS-B Is the Driving Force for Nucleo-Cytoplasmic Shuttling
por: Berndt, Nicole, et al.
Publicado: (2021)

Specific Y14 domains mediate its nucleo-cytoplasmic shuttling and association with spliced mRNA
por: Kataoka, Naoyuki, et al.
Publicado: (2011)

Beyond Kinase Activity: ERK5 Nucleo-Cytoplasmic Shuttling as a Novel Target for Anticancer Therapy
por: Tubita, Alessandro, et al.
Publicado: (2020)

Nucleo-cytoplasmic shuttling of 14-3-3 epsilon carrying hnRNP C promotes autophagy
por: Guo, Manlan, et al.
Publicado: (2023)

Ivermectin inhibits the sporogony of Plasmodium falciparum in Anopheles gambiae
por: Kobylinski, Kevin C, et al.
Publicado: (2012)

A Plasmodium falciparum protein tyrosine phosphatase inhibitor identified from the ChEMBL‐NTD database blocks parasite growth
por: Pandey, Rajan, et al.
Publicado: (2021)

Nucleo-cytoplasmic shuttling of murine RBPJ by Hairless protein matches that of Su(H) protein in the model system Drosophila melanogaster
por: Wolf, Dorina B., et al.
Publicado: (2021)

Plasmodium falciparum DDX17 is an RNA helicase crucial for parasite development
por: Sourabh, Suman, et al.
Publicado: (2021)

Plasmodium falciparum specific helicase 2 is a dual, bipolar helicase and is crucial for parasite growth
por: Chauhan, Manish, et al.
Publicado: (2019)

Genome wide in silico analysis of Plasmodium falciparum phosphatome
por: Pandey, Rajan, et al.
Publicado: (2014)

Biochemical characterization of Plasmodium falciparum parasite specific helicase 1 (PfPSH1)
por: Chauhan, Manish, et al.
Publicado: (2019)

Structural analysis of the SRP Alu domain from Plasmodium falciparum reveals a non-canonical open conformation
por: Soni, Komal, et al.
Publicado: (2021)

An integrated model for the nucleo-cytoplasmic transport of cytoplasmic poly(A)-binding proteins
por: Burgess, Hannah M., et al.
Publicado: (2012)

Enantioselective Synthesis of γ-Phenyl-γ-amino Vinyl Phosphonates and Sulfones and Their Application to the Synthesis of Novel Highly Potent Antimalarials
por: Aratikatla, Eswar K., et al.
Publicado: (2020)

Human Cyclophilin B forms part of a multi-protein complex during erythrocyte invasion by Plasmodium falciparum
por: Prakash, Prem, et al.
Publicado: (2017)

Nuclear annexin II negatively regulates growth of LNCaP cells and substitution of ser 11 and 25 to glu prevents nucleo-cytoplasmic shuttling of annexin II
por: Liu, Jie, et al.
Publicado: (2003)

Nucleo-cytoplasmic shuttling dynamics of the transcriptional regulators XYR1 and CRE1 under conditions of cellulase and xylanase gene expression in Trichoderma reesei
por: Lichius, Alexander, et al.
Publicado: (2014)

Unraveling the ‘DEAD-box’ helicases of Plasmodium falciparum
por: Tuteja, Renu, et al.
Publicado: (2006)

Nucleo-cytoplasmic transport of proteins and RNA in plants
por: Merkle, Thomas
Publicado: (2010)

Disruption of a mitochondrial protease machinery in Plasmodium falciparum is an intrinsic signal for parasite cell death
por: Rathore, S, et al.
Publicado: (2011)

Conservation of Importin α Function in Apicomplexans: Ivermectin and GW5074 Target Plasmodium falciparum Importin α and Inhibit Parasite Growth in Culture
por: Walunj, Sujata B., et al.
Publicado: (2022)

Widespread occurrence of lysine methylation in Plasmodium falciparum proteins at asexual blood stages
por: Kaur, Inderjeet, et al.
Publicado: (2016)

Regulation of AUXIN RESPONSE FACTOR condensation and nucleo-cytoplasmic partitioning
por: Jing, Hongwei, et al.
Publicado: (2022)

Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth
por: Tarique, Mohammed, et al.
Publicado: (2014)

Glycosphingolipid GM3 is localized in both exoplasmic and cytoplasmic leaflets of Plasmodium falciparum malaria parasite plasma membrane
por: Koudatsu, Shiomi, et al.
Publicado: (2021)

Nucleo-cytoplasmic transport as a therapeutic target of cancer
por: Gravina, Giovanni Luca, et al.
Publicado: (2014)

Nucleo–cytoplasmic transport defects and protein aggregates in neurodegeneration
por: Bitetto, Giacomo, et al.
Publicado: (2020)

Immunity against sexual stage Plasmodium falciparum and Plasmodium vivax parasites
por: de Jong, Roos M., et al.
Publicado: (2019)

Biogenesis of the Signal Recognition Particle (Srp) Involves Import of Srp Proteins into the Nucleolus, Assembly with the Srp-Rna, and Xpo1p-Mediated Export
por: Grosshans, Helge, et al.
Publicado: (2001)

Nucleo-cytoplasmic shuttling of the endonuclease ankyrin repeats and LEM domain-containing protein 1 (Ankle1) is mediated by canonical nuclear export- and nuclear import signals
por: Zlopasa, Livija, et al.
Publicado: (2016)

Heterogeneity in prevalence of subclinical Plasmodium falciparum and Plasmodium vivax infections but no parasite genomic clustering in the Chittagong Hill Tracts, Bangladesh
por: Huwe, Tiffany, et al.
Publicado: (2022)

A genome-wide analysis of coatomer protein (COP) subunits of apicomplexan parasites and their evolutionary relationships
por: Kibria, K. M. Kaderi, et al.
Publicado: (2019)

Polyamine uptake in the malaria parasite, Plasmodium falciparum, is dependent on the parasite's membrane potential
por: Niemand, J, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_7jsl8crumdtskg68ane6kr3sk6