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A positive feedback loop between EBP2 and c-Myc regulates rDNA transcription, cell proliferation, and tumorigenesis

The oncoprotein c-Myc is a key transcription factor with essential functions in the nucleolus (NO) to regulate ribosomal RNA (rRNA) synthesis, ribosome biogenesis, and cell proliferation. Yet, the mechanism that regulates the distribution and function of nucleolar c-Myc is still not completely under...

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Detalles Bibliográficos
Autores principales:	Liao, P, Wang, W, Shen, M, Pan, W, Zhang, K, Wang, R, Chen, T, Chen, Y, Chen, H, Wang, P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040698/ https://www.ncbi.nlm.nih.gov/pubmed/24481446 http://dx.doi.org/10.1038/cddis.2013.536

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