ROS-PIASγ cross talk channelizes ATM signaling from resistance to apoptosis during chemosensitization of resistant tumors

With the existing knowledge of ATM's role in therapeutic resistance, the present study aimed at identifying the molecular mechanisms that influence ATM to oscillate between chemoresistance and chemosensitivity. We observed that the redox status of tumors functions as a major determinant of ATM-...

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Detalles Bibliográficos
Autores principales: Mohanty, S, Saha, S, Md S Hossain, D, Adhikary, A, Mukherjee, S, Manna, A, Chakraborty, S, Mazumdar, M, Ray, P, Das, K, Chakraborty, J, Sa, G, Das, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040699/
https://www.ncbi.nlm.nih.gov/pubmed/24457965
http://dx.doi.org/10.1038/cddis.2013.534

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