Cargando…

CDK5-induced p-PPARγ(Ser 112) downregulates GFAP via PPREs in developing rat brain: effect of metal mixture and troglitazone in astrocytes

The peroxisome proliferator-activated receptor gamma (PPARγ), a group of ligand-activated transcriptional factors, is expressed in glial fibrillary acidic protein (GFAP)-immunoreactive astrocytes. Here, we investigated the role of PPARγ in regulating GFAP using a mixture of As, Cd and Pb (metal mixt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rai, A, Tripathi, S, Kushwaha, R, Singh, P, Srivastava, P, Sanyal, S, Bandyopadhyay, S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040704/ https://www.ncbi.nlm.nih.gov/pubmed/24481447 http://dx.doi.org/10.1038/cddis.2013.514

Ejemplares similares

PPARγ phase separates with RXRα at PPREs to regulate target gene expression
por: Li, Zhean, et al.
Publicado: (2022)

GFAP expression in injured astrocytes in rats
por: Zhang, Shuquan, et al.
Publicado: (2017)

Troglitazone suppresses tumor cell growth and glutamine metabolism through a PPAR-independent mechanism
por: Reynolds, Miriam, et al.
Publicado: (2014)

Troglitazone suppresses telomerase activity independently of PPARγ in estrogen-receptor negative breast cancer cells
por: Rashid-Kolvear, Fariborz, et al.
Publicado: (2010)

Beyond the GFAP-Astrocyte Protein Markers in the Brain
por: Jurga, Agnieszka M., et al.
Publicado: (2021)

Identification of genes associated with the astrocyte-specific gene Gfap during astrocyte differentiation
por: Ito, Kenji, et al.
Publicado: (2016)

Olig2-Lineage Astrocytes: A Distinct Subtype of Astrocytes That Differs from GFAP Astrocytes
por: Tatsumi, Kouko, et al.
Publicado: (2018)

Troglitazone and Δ2Troglitazone Enhance Adiponectin Expression in Monocytes/Macrophages through the AMP-Activated Protein Kinase Pathway
por: Tsai, Jaw-Shiun, et al.
Publicado: (2014)

PPARγ activation by troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux
por: Nazim, Uddin MD., et al.
Publicado: (2017)

In vitro and in vivo cytotoxicity of troglitazone in pancreatic cancer
por: Fujita, Megumi, et al.
Publicado: (2017)

New Insights into GFAP Negative Astrocytes in Calbindin D28k Immunoreactive Astrocytes
por: Xu, Jie
Publicado: (2018)

Mutations in GFAP Disrupt the Distribution and Function of Organelles in Human Astrocytes
por: Jones, Jeffrey R., et al.
Publicado: (2018)

Troglitazone, a PPAR-γ activator prevents endothelial cell adhesion molecule expression and lymphocyte adhesion mediated by TNF-α
por: Sasaki, Makoto, et al.
Publicado: (2005)

Troglitazone Attenuates TGF-β1-Induced EMT in Alveolar Epithelial Cells via a PPARγ-Independent Mechanism
por: Zhou, Beiyun, et al.
Publicado: (2012)

The PPAR Gamma Agonist Troglitazone Regulates Erk 1/2 Phosphorylation via a PPARγ-Independent, MEK-Dependent Pathway in Human Prostate Cancer Cells
por: Bolden, Adrienne, et al.
Publicado: (2012)

Effect of troglitazone on radiation sensitivity in cervix cancer cells
por: An, Zhengzhe, et al.
Publicado: (2012)

Age, environment, object recognition and morphological diversity of GFAP-immunolabeled astrocytes
por: Diniz, Daniel Guerreiro, et al.
Publicado: (2016)

In Vivo Two-Photon Imaging of Astrocytes in GFAP-GFP Transgenic Mice
por: Guo, Dongjun, et al.
Publicado: (2017)

Automated detection of GFAP-labeled astrocytes in micrographs using YOLOv5
por: Huang, Yewen, et al.
Publicado: (2022)

Immunoreactivity to astrocytes in different forms of dementia: High prevalence of autoantibodies to GFAP
por: Barthel, Paula Charlotte, et al.
Publicado: (2023)

The antidiabetic drug troglitazone protects against PrP (106–126)-induced neurotoxicity via the PPARγ-autophagy pathway in neuronal cells
por: Moon, Ji-Hong, et al.
Publicado: (2021)

Troglitazone reverses the multiple drug resistance phenotype in cancer cells
por: Davies, Gerald F, et al.
Publicado: (2009)

Troglitazone and tumor inhibition: an evolving concept in the management of systemic malignancies
por: Kapoor, Shailendra
Publicado: (2012)

Housing Complexity Alters GFAP-Immunoreactive Astrocyte Morphology in the Rat Dentate Gyrus
por: Salois, Garrick, et al.
Publicado: (2016)

Altered Astrocytic Swelling in the Cortex of α-Syntrophin-Negative GFAP/EGFP Mice
por: Anderova, Miroslava, et al.
Publicado: (2014)

Methimazole Inhibits the Expression of GFAP and the Migration of Astrocyte in Scratched Wound Model In Vitro
por: Zhao, Lina, et al.
Publicado: (2020)

Inhibition of cell motility by troglitazone in human ovarian carcinoma cell line
por: Yang, Yuh-Cheng, et al.
Publicado: (2007)

Antiproliferative effects and molecular mechanisms of troglitazone in human cervical cancer in vitro
por: Ye, Jinjun, et al.
Publicado: (2015)

A Retrospective Review of Thiazolidinediones with Development of a Troglitazone Conversion Protocol
por: Lindsey, Cameron, et al.
Publicado: (2003)

Correction: Altered Astrocytic Swelling in the Cortex of α-Syntrophin-Negative GFAP/EGFP Mice
Publicado: (2015)

Enhanced Expression of Markers for Astrocytes in the Brain of a Line of GFAP-TK Transgenic Mice
por: Zhang, Xiaoqin, et al.
Publicado: (2017)

Pressure-Induced Changes in Astrocyte GFAP, Actin, and Nuclear Morphology in Mouse Optic Nerve
por: Ling, Yik Tung Tracy, et al.
Publicado: (2020)

Distribution of GFAP in Squamata: Extended Immunonegative Areas, Astrocytes, High Diversity, and Their Bearing on Evolution
por: Lõrincz, Dávid, et al.
Publicado: (2020)

Astrocyte Specificity and Coverage of hGFAP-CreERT2 [Tg(GFAP-Cre/ERT2)13Kdmc] Mouse Line in Various Brain Regions
por: Park, Yongmin Mason, et al.
Publicado: (2018)

GFAP at 50
por: Messing, Albee, et al.
Publicado: (2020)

Troglitazone Induces Extracellular Matrix and Cytoskeleton Remodeling in Mouse Collecting Duct Cells
por: Corinaldi, Jaime, et al.
Publicado: (2012)

Gfap and Osmr regulation by BRG1 and STAT3 via interchromosomal gene clustering in astrocytes
por: Ito, Kenji, et al.
Publicado: (2018)

Erratum in: Pressure-Induced Changes in Astrocyte GFAP, Actin, and Nuclear Morphology in Mouse Optic Nerve
Publicado: (2020)

Increases in GFAP immunoreactive astrocytes in the cerebellar molecular layer of young adult CBA/J mice
por: Tyszkiewicz, Cheryl, et al.
Publicado: (2021)

CSF GFAP levels in double seronegative neuromyelitis optica spectrum disorder: no evidence of astrocyte damage
por: Hyun, Jae-Won, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7pq0ahba56drgo34asplort373