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Control of glioma cell death and differentiation by PKM2–Oct4 interaction

Glioma stem cells are highly resistant to cell death and as such are supposed to contribute to tumor recurrence by eluding anticancer treatments. Here, we show that spheroids that contain rat neural stem cells (NSCs) or rat glioma stem cells (cancer stem cells, CSCs) express isoforms 1 and 2 of pyru...

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Detalles Bibliográficos
Autores principales: Morfouace, M, Lalier, L, Oliver, L, Cheray, M, Pecqueur, C, Cartron, P-F, Vallette, F M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040711/
https://www.ncbi.nlm.nih.gov/pubmed/24481450
http://dx.doi.org/10.1038/cddis.2013.561