Re-examining how complexin inhibits neurotransmitter release

Complexins play activating and inhibitory functions in neurotransmitter release. The complexin accessory helix inhibits release and was proposed to insert into SNARE complexes to prevent their full assembly. This model was supported by ‘superclamp’ and ‘poor-clamp’ mutations that enhanced or decreas...

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Detalles Bibliográficos
Autores principales: Trimbuch, Thorsten, Xu, Junjie, Flaherty, David, Tomchick, Diana R, Rizo, Josep, Rosenmund, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040926/
https://www.ncbi.nlm.nih.gov/pubmed/24842998
http://dx.doi.org/10.7554/eLife.02391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040926/
https://www.ncbi.nlm.nih.gov/pubmed/24842998
http://dx.doi.org/10.7554/eLife.02391

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