cAMP Signaling Affects Irreversible Attachment During Biofilm Formation by Pseudomonas aeruginosa PAO1

Pseudomonas aeruginosa responds to environmental changes and regulates its life cycle from planktonic to biofilm modes of growth. The control of cell attachment to surfaces is one of the critical processes that determine this transition. Environmental signals are typically relayed to the cytoplasm b...

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Detalles Bibliográficos
Autores principales: Ono, Kaori, Oka, Rie, Toyofuku, Masanori, Sakaguchi, Ayane, Hamada, Masakaze, Yoshida, Shiomi, Nomura, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Microbial Ecology/The Japanese Society of Soil Microbiology 2014
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041239/
https://www.ncbi.nlm.nih.gov/pubmed/24553108
http://dx.doi.org/10.1264/jsme2.ME13151
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author Ono, Kaori
Oka, Rie
Toyofuku, Masanori
Sakaguchi, Ayane
Hamada, Masakaze
Yoshida, Shiomi
Nomura, Nobuhiko
author_facet Ono, Kaori
Oka, Rie
Toyofuku, Masanori
Sakaguchi, Ayane
Hamada, Masakaze
Yoshida, Shiomi
Nomura, Nobuhiko
author_sort Ono, Kaori
collection PubMed
description Pseudomonas aeruginosa responds to environmental changes and regulates its life cycle from planktonic to biofilm modes of growth. The control of cell attachment to surfaces is one of the critical processes that determine this transition. Environmental signals are typically relayed to the cytoplasm by second messenger systems. We here demonstrated that the second messenger, cAMP, regulated the attachment of cells. Our results suggest cAMP inhibited the transition from reversible to irreversible attachment. Further analyses revealed that cell surface hydrophobicity, one of the key factors in cell attachment, was altered by cAMP.
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spelling pubmed-40412392014-07-24 cAMP Signaling Affects Irreversible Attachment During Biofilm Formation by Pseudomonas aeruginosa PAO1 Ono, Kaori Oka, Rie Toyofuku, Masanori Sakaguchi, Ayane Hamada, Masakaze Yoshida, Shiomi Nomura, Nobuhiko Microbes Environ Short Communication Pseudomonas aeruginosa responds to environmental changes and regulates its life cycle from planktonic to biofilm modes of growth. The control of cell attachment to surfaces is one of the critical processes that determine this transition. Environmental signals are typically relayed to the cytoplasm by second messenger systems. We here demonstrated that the second messenger, cAMP, regulated the attachment of cells. Our results suggest cAMP inhibited the transition from reversible to irreversible attachment. Further analyses revealed that cell surface hydrophobicity, one of the key factors in cell attachment, was altered by cAMP. Japanese Society of Microbial Ecology/The Japanese Society of Soil Microbiology 2014-03 2014-02-19 /pmc/articles/PMC4041239/ /pubmed/24553108 http://dx.doi.org/10.1264/jsme2.ME13151 Text en Copyright © 2014 by the Japanese Society of Microbial Ecology / the Japanese Society of Soil Microbiology http://creativecommons.org/licenses/by/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Ono, Kaori
Oka, Rie
Toyofuku, Masanori
Sakaguchi, Ayane
Hamada, Masakaze
Yoshida, Shiomi
Nomura, Nobuhiko
cAMP Signaling Affects Irreversible Attachment During Biofilm Formation by Pseudomonas aeruginosa PAO1
title cAMP Signaling Affects Irreversible Attachment During Biofilm Formation by Pseudomonas aeruginosa PAO1
title_full cAMP Signaling Affects Irreversible Attachment During Biofilm Formation by Pseudomonas aeruginosa PAO1
title_fullStr cAMP Signaling Affects Irreversible Attachment During Biofilm Formation by Pseudomonas aeruginosa PAO1
title_full_unstemmed cAMP Signaling Affects Irreversible Attachment During Biofilm Formation by Pseudomonas aeruginosa PAO1
title_short cAMP Signaling Affects Irreversible Attachment During Biofilm Formation by Pseudomonas aeruginosa PAO1
title_sort camp signaling affects irreversible attachment during biofilm formation by pseudomonas aeruginosa pao1
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041239/
https://www.ncbi.nlm.nih.gov/pubmed/24553108
http://dx.doi.org/10.1264/jsme2.ME13151
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