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Phosphorylation of mTOR and S6RP predicts the efficacy of everolimus in patients with metastatic renal cell carcinoma

BACKGROUND: The incidence of renal cell cancer (RCC) has been increasing for the past decade, and the 5-year survival for patients with metastatic RCC (mRCC) is rather low. Everolimus (RAD001), a new inhibitor for mammalian target of rapamycin (mTOR), is generally well tolerated, and demonstrates cl...

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Detalles Bibliográficos
Autores principales:	Li, Siming, Kong, Yan, Si, Lu, Chi, Zhihong, Cui, Chuanliang, Sheng, Xinan, Guo, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041340/ https://www.ncbi.nlm.nih.gov/pubmed/24886512 http://dx.doi.org/10.1186/1471-2407-14-376

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