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A piggyBac-based reporter system for scalable in vitro and in vivo analysis of 3′ untranslated region-mediated gene regulation

Regulation of messenger ribonucleic acid (mRNA) subcellular localization, stability and translation is a central aspect of gene expression. Much of this control is mediated via recognition of mRNA 3′ untranslated regions (UTRs) by microRNAs (miRNAs) and RNA-binding proteins. The gold standard approa...

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Detalles Bibliográficos
Autores principales: Chaudhury, Arindam, Kongchan, Natee, Gengler, Jon P., Mohanty, Vakul, Christiansen, Audrey E., Fachini, Joseph M., Martin, James F., Neilson, Joel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041432/
https://www.ncbi.nlm.nih.gov/pubmed/24753411
http://dx.doi.org/10.1093/nar/gku258