Mechanism of oxidant-induced mistranslation by threonyl-tRNA synthetase

Aminoacyl-tRNA synthetases maintain the fidelity during protein synthesis by selective activation of cognate amino acids at the aminoacylation site and hydrolysis of misformed aminoacyl-tRNAs at the editing site. Threonyl-tRNA synthetase (ThrRS) misactivates serine and utilizes an editing site cyste...

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Detalles Bibliográficos
Autores principales: Wu, Jiang, Fan, Yongqiang, Ling, Jiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041444/
https://www.ncbi.nlm.nih.gov/pubmed/24744241
http://dx.doi.org/10.1093/nar/gku271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041444/
https://www.ncbi.nlm.nih.gov/pubmed/24744241
http://dx.doi.org/10.1093/nar/gku271

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