RalR (a DNase) and RalA (a small RNA) form a type I toxin–antitoxin system in Escherichia coli

For toxin/antitoxin (TA) systems, no toxin has been identified that functions by cleaving DNA. Here, we demonstrate that RalR and RalA of the cryptic prophage rac form a type I TA pair in which the antitoxin RNA is a trans-encoded small RNA with 16 nucleotides of complementarity to the toxin mRNA. W...

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Detalles Bibliográficos
Autores principales: Guo, Yunxue, Quiroga, Cecilia, Chen, Qin, McAnulty, Michael J., Benedik, Michael J., Wood, Thomas K., Wang, Xiaoxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041452/
https://www.ncbi.nlm.nih.gov/pubmed/24748661
http://dx.doi.org/10.1093/nar/gku279

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