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Genome-wide RNA-binding analysis of the trypanosome U1 snRNP proteins U1C and U1-70K reveals cis/trans-spliceosomal network

Trans-splicing in trypanosomes adds a 39-nucleotide mini-exon from the spliced leader (SL) RNA to the 5′ end of each protein-coding sequence. On the other hand, cis-splicing of the few intron-containing genes requires the U1 small nuclear ribonucleoprotein (snRNP) particle. To search for potential n...

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Detalles Bibliográficos
Autores principales: Preußer, Christian, Rossbach, Oliver, Hung, Lee-Hsueh, Li, Dan, Bindereif, Albrecht
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041458/
https://www.ncbi.nlm.nih.gov/pubmed/24748659
http://dx.doi.org/10.1093/nar/gku286