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Cas6 specificity and CRISPR RNA loading in a complex CRISPR-Cas system

CRISPR-Cas is an adaptive prokaryotic immune system, providing protection against viruses and other mobile genetic elements. In type I and type III CRISPR-Cas systems, CRISPR RNA (crRNA) is generated by cleavage of a primary transcript by the Cas6 endonuclease and loaded into multisubunit surveillan...

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Detalles Bibliográficos
Autores principales:	Sokolowski, Richard D., Graham, Shirley, White, Malcolm F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2014
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041471/ https://www.ncbi.nlm.nih.gov/pubmed/24753403 http://dx.doi.org/10.1093/nar/gku308

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