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The Diacylglycerol Kinase α/Atypical PKC/β1 Integrin Pathway in SDF-1α Mammary Carcinoma Invasiveness
Diacylglycerol kinase α (DGKα), by phosphorylating diacylglycerol into phosphatidic acid, provides a key signal driving cell migration and matrix invasion. We previously demonstrated that in epithelial cells activation of DGKα activity promotes cytoskeletal remodeling and matrix invasion by recruiti...
Autores principales: | Rainero, Elena, Cianflone, Cristina, Porporato, Paolo Ettore, Chianale, Federica, Malacarne, Valeria, Bettio, Valentina, Ruffo, Elisa, Ferrara, Michele, Benecchia, Fabio, Capello, Daniela, Paster, Wolfgang, Locatelli, Irene, Bertoni, Alessandra, Filigheddu, Nicoletta, Sinigaglia, Fabiola, Norman, Jim C., Baldanzi, Gianluca, Graziani, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041662/ https://www.ncbi.nlm.nih.gov/pubmed/24887021 http://dx.doi.org/10.1371/journal.pone.0097144 |
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