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Design and Analysis of a Petri Net Model of the Von Hippel-Lindau (VHL) Tumor Suppressor Interaction Network

Von Hippel-Lindau (VHL) syndrome is a hereditary condition predisposing to the development of different cancer forms, related to germline inactivation of the homonymous tumor suppressor pVHL. The best characterized function of pVHL is the ubiquitination dependent degradation of Hypoxia Inducible Fac...

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Detalles Bibliográficos
Autores principales:	Minervini, Giovanni, Panizzoni, Elisabetta, Giollo, Manuel, Masiero, Alessandro, Ferrari, Carlo, Tosatto, Silvio C. E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041725/ https://www.ncbi.nlm.nih.gov/pubmed/24886840 http://dx.doi.org/10.1371/journal.pone.0096986

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