A Non-Canonical NRPS Is Involved in the Synthesis of Fungisporin and Related Hydrophobic Cyclic Tetrapeptides in Penicillium chrysogenum

The filamentous fungus Penicillium chrysogenum harbors an astonishing variety of nonribosomal peptide synthetase genes, which encode proteins known to produce complex bioactive metabolites from simple building blocks. Here we report a novel non-canonical tetra-modular nonribosomal peptide synthetase...

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Detalles Bibliográficos
Autores principales: Ali, Hazrat, Ries, Marco I., Lankhorst, Peter P., van der Hoeven, Rob A. M., Schouten, Olaf L., Noga, Marek, Hankemeier, Thomas, van Peij, Noël N. M. E., Bovenberg, Roel A. L., Vreeken, Rob J., Driessen, Arnold J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041764/
https://www.ncbi.nlm.nih.gov/pubmed/24887561
http://dx.doi.org/10.1371/journal.pone.0098212

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