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Stereoselective Property of 20(S)-Protopanaxadiol Ocotillol Type Epimers Affects Its Absorption and Also the Inhibition of P-Glycoprotein

Stereoselectivity has been proved to be tightly related to drug action including pharmacodynamics and pharmacokinetics. (20S,24R)-epoxy-dammarane-3,12,25-triol (24R-epimer) and (20S,24S)-epoxy-dammarane-3,12,25-triol (24S-epimer), a pair of 20(S)-protopanaxadiol (PPD) ocotillol type epimers, were th...

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Detalles Bibliográficos
Autores principales:	Wang, Wenyan, Wu, Xiangmeng, Wang, Li, Meng, Qingguo, Liu, Wanhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041784/ https://www.ncbi.nlm.nih.gov/pubmed/24887182 http://dx.doi.org/10.1371/journal.pone.0098887

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