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Protective Epitopes of the Plasmodium falciparum SERA5 Malaria Vaccine Reside in Intrinsically Unstructured N-Terminal Repetitive Sequences
The malaria vaccine candidate antigen, SE36, is based on the N-terminal 47 kDa domain of Plasmodium falciparum serine repeat antigen 5 (SERA5). In epidemiological studies, we have previously shown the inhibitory effects of SE36 specific antibodies on in vitro parasite growth and the negative correla...
Autores principales: | Yagi, Masanori, Bang, Gilles, Tougan, Takahiro, Palacpac, Nirianne M. Q., Arisue, Nobuko, Aoshi, Taiki, Matsumoto, Yoshitsugu, Ishii, Ken J., Egwang, Thomas G., Druilhe, Pierre, Horii, Toshihiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041889/ https://www.ncbi.nlm.nih.gov/pubmed/24886718 http://dx.doi.org/10.1371/journal.pone.0098460 |
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