Gene expression profiling of 49 human tumor xenografts from in vitro culture through multiple in vivo passages - strategies for data mining in support of therapeutic studies

BACKGROUND: Development of cancer therapeutics partially depends upon selection of appropriate animal models. Therefore, improvements to model selection are beneficial. RESULTS: Forty-nine human tumor xenografts at in vivo passages 1, 4 and 10 were subjected to cDNA microarray analysis yielding a da...

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Detalles Bibliográficos
Autores principales: Hollingshead, Melinda G, Stockwin, Luke H, Alcoser, Sergio Y, Newton, Dianne L, Orsburn, Benjamin C, Bonomi, Carrie A, Borgel, Suzanne D, Divelbiss, Raymond, Dougherty, Kelly M, Hager, Elizabeth J, Holbeck, Susan L, Kaur, Gurmeet, Kimmel, David J, Kunkel, Mark W, Millione, Angelena, Mullendore, Michael E, Stotler, Howard, Collins, Jerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041995/
https://www.ncbi.nlm.nih.gov/pubmed/24885658
http://dx.doi.org/10.1186/1471-2164-15-393

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