Comparison and phylogenetic analysis based on the B2L gene of orf virus from goats and sheep in China during 2009-2011

As a zoonotic infectious disease, orf outbreaks have been reported in China in recent years. However, molecular epidemiology analysis has not been performed for Chinese orf virus (ORFV) strains. Here, we have identified 13 ORFVs from goats and sheep in China between 2009 and 2011. Thirty-four comple...

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Detalles Bibliográficos
Autores principales: Zhang, Keshan, Liu, Yongjie, Kong, Hanjin, Shang, Youjun, Liu, Xiangtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2013
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042016/
https://www.ncbi.nlm.nih.gov/pubmed/24343266
http://dx.doi.org/10.1007/s00705-013-1946-6
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author Zhang, Keshan
Liu, Yongjie
Kong, Hanjin
Shang, Youjun
Liu, Xiangtao
author_facet Zhang, Keshan
Liu, Yongjie
Kong, Hanjin
Shang, Youjun
Liu, Xiangtao
author_sort Zhang, Keshan
collection PubMed
description As a zoonotic infectious disease, orf outbreaks have been reported in China in recent years. However, molecular epidemiology analysis has not been performed for Chinese orf virus (ORFV) strains. Here, we have identified 13 ORFVs from goats and sheep in China between 2009 and 2011. Thirty-four complete B2L sequences were used to construct a phylogenetic tree to elucidate the molecular epidemiology of ORFV in China. Nucleotide sequences of B2L genes of clinical samples and attenuated vaccine strains were aligned and compared. Three genotypes were found by molecular epidemiology analysis. Amino acid substitutions were dispersed among B2 polypeptides from wild and attenuated ORFV strains. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00705-013-1946-6) contains supplementary material, which is available to authorized users.
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spelling pubmed-40420162014-06-18 Comparison and phylogenetic analysis based on the B2L gene of orf virus from goats and sheep in China during 2009-2011 Zhang, Keshan Liu, Yongjie Kong, Hanjin Shang, Youjun Liu, Xiangtao Arch Virol Brief Report As a zoonotic infectious disease, orf outbreaks have been reported in China in recent years. However, molecular epidemiology analysis has not been performed for Chinese orf virus (ORFV) strains. Here, we have identified 13 ORFVs from goats and sheep in China between 2009 and 2011. Thirty-four complete B2L sequences were used to construct a phylogenetic tree to elucidate the molecular epidemiology of ORFV in China. Nucleotide sequences of B2L genes of clinical samples and attenuated vaccine strains were aligned and compared. Three genotypes were found by molecular epidemiology analysis. Amino acid substitutions were dispersed among B2 polypeptides from wild and attenuated ORFV strains. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00705-013-1946-6) contains supplementary material, which is available to authorized users. Springer Vienna 2013-12-17 2014 /pmc/articles/PMC4042016/ /pubmed/24343266 http://dx.doi.org/10.1007/s00705-013-1946-6 Text en © The Author(s) 2013 https://creativecommons.org/licenses/by/2.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Brief Report
Zhang, Keshan
Liu, Yongjie
Kong, Hanjin
Shang, Youjun
Liu, Xiangtao
Comparison and phylogenetic analysis based on the B2L gene of orf virus from goats and sheep in China during 2009-2011
title Comparison and phylogenetic analysis based on the B2L gene of orf virus from goats and sheep in China during 2009-2011
title_full Comparison and phylogenetic analysis based on the B2L gene of orf virus from goats and sheep in China during 2009-2011
title_fullStr Comparison and phylogenetic analysis based on the B2L gene of orf virus from goats and sheep in China during 2009-2011
title_full_unstemmed Comparison and phylogenetic analysis based on the B2L gene of orf virus from goats and sheep in China during 2009-2011
title_short Comparison and phylogenetic analysis based on the B2L gene of orf virus from goats and sheep in China during 2009-2011
title_sort comparison and phylogenetic analysis based on the b2l gene of orf virus from goats and sheep in china during 2009-2011
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042016/
https://www.ncbi.nlm.nih.gov/pubmed/24343266
http://dx.doi.org/10.1007/s00705-013-1946-6
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