Treatment options for patients with large cell neuroendocrine carcinoma of the lung

Large cell neuroendocrine carcinoma (LCNEC) of the lung is categorized as a variant of large cell carcinomas, and LCNEC tumors display biological behaviors resembling those of small cell lung carcinomas and features of high-grade neuroendocrine tumors. Because patients with LCNEC have a poor prognos...

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Autores principales: Iyoda, Akira, Makino, Takashi, Koezuka, Satoshi, Otsuka, Hajime, Hata, Yoshinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2014
Materias:
Current Topics Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042022/
https://www.ncbi.nlm.nih.gov/pubmed/24719260
http://dx.doi.org/10.1007/s11748-014-0379-9
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author Iyoda, Akira
Makino, Takashi
Koezuka, Satoshi
Otsuka, Hajime
Hata, Yoshinobu
author_facet Iyoda, Akira
Makino, Takashi
Koezuka, Satoshi
Otsuka, Hajime
Hata, Yoshinobu
author_sort Iyoda, Akira
collection PubMed
description Large cell neuroendocrine carcinoma (LCNEC) of the lung is categorized as a variant of large cell carcinomas, and LCNEC tumors display biological behaviors resembling those of small cell lung carcinomas and features of high-grade neuroendocrine tumors. Because patients with LCNEC have a poor prognosis, surgery alone is not sufficient. Multimodality therapies, including adjuvant chemotherapy, appear promising for improved prognosis in patients with LCNEC. In this review article, we discuss treatment options for patients with LCNEC of the lung.
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spelling pubmed-40420222014-06-18 Treatment options for patients with large cell neuroendocrine carcinoma of the lung Iyoda, Akira Makino, Takashi Koezuka, Satoshi Otsuka, Hajime Hata, Yoshinobu Gen Thorac Cardiovasc Surg Current Topics Review Article Large cell neuroendocrine carcinoma (LCNEC) of the lung is categorized as a variant of large cell carcinomas, and LCNEC tumors display biological behaviors resembling those of small cell lung carcinomas and features of high-grade neuroendocrine tumors. Because patients with LCNEC have a poor prognosis, surgery alone is not sufficient. Multimodality therapies, including adjuvant chemotherapy, appear promising for improved prognosis in patients with LCNEC. In this review article, we discuss treatment options for patients with LCNEC of the lung. Springer Japan 2014-04-10 2014 /pmc/articles/PMC4042022/ /pubmed/24719260 http://dx.doi.org/10.1007/s11748-014-0379-9 Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Current Topics Review Article
Iyoda, Akira
Makino, Takashi
Koezuka, Satoshi
Otsuka, Hajime
Hata, Yoshinobu
Treatment options for patients with large cell neuroendocrine carcinoma of the lung
title Treatment options for patients with large cell neuroendocrine carcinoma of the lung
title_full Treatment options for patients with large cell neuroendocrine carcinoma of the lung
title_fullStr Treatment options for patients with large cell neuroendocrine carcinoma of the lung
title_full_unstemmed Treatment options for patients with large cell neuroendocrine carcinoma of the lung
title_short Treatment options for patients with large cell neuroendocrine carcinoma of the lung
title_sort treatment options for patients with large cell neuroendocrine carcinoma of the lung
topic Current Topics Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042022/
https://www.ncbi.nlm.nih.gov/pubmed/24719260
http://dx.doi.org/10.1007/s11748-014-0379-9
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