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Built for speed: Molecular properties of the voltage sensor domain underlie the rapid activation of voltage-gated Na(+) channels compared with Shaker-type K(+) channels
Many of us were taught in high school biology that the action potential waveform in nerves and other excitable tissues was generated by an initial rapid influx of external Na(+) ions across the plasma membrane, followed by an outward movement of intracellular K(+) ions. The former event, mediated by...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042476/ https://www.ncbi.nlm.nih.gov/pubmed/24366114 http://dx.doi.org/10.4161/chan.27652 |