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Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus
Group B Streptococcus (GBS) causes invasive infections in human newborns. We recently showed that the GBS β-protein attenuates innate immune responses by binding to sialic acid–binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory receptor on phagocytes. Interestingly, neutrophils and monoc...
Autores principales: | Ali, Syed Raza, Fong, Jerry J., Carlin, Aaron F., Busch, Tamara D., Linden, Rebecka, Angata, Takashi, Areschoug, Thomas, Parast, Mana, Varki, Nissi, Murray, Jeffrey, Nizet, Victor, Varki, Ajit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042635/ https://www.ncbi.nlm.nih.gov/pubmed/24799499 http://dx.doi.org/10.1084/jem.20131853 |
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