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12-hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor
Leukotriene B(4) (LTB(4)) receptor type 2 (BLT2) is a G protein–coupled receptor (GPCR) for 12(S)-hydroxyheptadeca-5Z,8E,10E-trienoic acid (12-HHT) and LTB(4). Despite the well-defined proinflammatory roles of BLT1, the in vivo functions of BLT2 remain elusive. As mouse BLT2 is highly expressed in e...
Autores principales: | Liu, Min, Saeki, Kazuko, Matsunobu, Takehiko, Okuno, Toshiaki, Koga, Tomoaki, Sugimoto, Yukihiko, Yokoyama, Chieko, Nakamizo, Satoshi, Kabashima, Kenji, Narumiya, Shuh, Shimizu, Takao, Yokomizo, Takehiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042643/ https://www.ncbi.nlm.nih.gov/pubmed/24821912 http://dx.doi.org/10.1084/jem.20132063 |
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