Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells

In mammals, the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II consists of 52 conserved heptapeptide repeats containing the consensus sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Post-translational modifications of the CTD coordinate the transcription cycle and various steps of mRNA matura...

Descripción completa

Detalles Bibliográficos
Autores principales: Descostes, Nicolas, Heidemann, Martin, Spinelli, Lionel, Schüller, Roland, Maqbool, Muhammad Ahmad, Fenouil, Romain, Koch, Frederic, Innocenti, Charlène, Gut, Marta, Gut, Ivo, Eick, Dirk, Andrau, Jean-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042876/
https://www.ncbi.nlm.nih.gov/pubmed/24842994
http://dx.doi.org/10.7554/eLife.02105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042876/
https://www.ncbi.nlm.nih.gov/pubmed/24842994
http://dx.doi.org/10.7554/eLife.02105

Ejemplares similares