Cargando…

Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells

In mammals, the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II consists of 52 conserved heptapeptide repeats containing the consensus sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Post-translational modifications of the CTD coordinate the transcription cycle and various steps of mRNA matura...

Descripción completa

Detalles Bibliográficos
Autores principales:	Descostes, Nicolas, Heidemann, Martin, Spinelli, Lionel, Schüller, Roland, Maqbool, Muhammad Ahmad, Fenouil, Romain, Koch, Frederic, Innocenti, Charlène, Gut, Marta, Gut, Ivo, Eick, Dirk, Andrau, Jean-Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Genes and Chromosomes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042876/ https://www.ncbi.nlm.nih.gov/pubmed/24842994 http://dx.doi.org/10.7554/eLife.02105

Ejemplares similares

Site-specific methylation and acetylation of lysine residues in the C-terminal domain (CTD) of RNA polymerase II
por: Voss, Kirsten, et al.
Publicado: (2015)

CpG islands and GC content dictate nucleosome depletion in a transcription-independent manner at mammalian promoters
por: Fenouil, Romain, et al.
Publicado: (2012)

Promoter nucleosome dynamics regulated by signalling through the CTD code
por: Materne, Philippe, et al.
Publicado: (2015)

Tyrosine-1 and threonine-4 phosphorylation marks complete the RNA polymerase II CTD phospho-code
por: Heidemann, Martin, et al.
Publicado: (2012)

Natural antisense transcripts regulate the neuronal stress response and excitability
por: Zheng, Xingguo, et al.
Publicado: (2014)

Dynamic recruitment of Ets1 to both nucleosome-occupied and -depleted enhancer regions mediates a transcriptional program switch during early T-cell differentiation
por: Cauchy, Pierre, et al.
Publicado: (2016)

ParB dynamics and the critical role of the CTD in DNA condensation unveiled by combined force-fluorescence measurements
por: Madariaga-Marcos, Julene, et al.
Publicado: (2019)

Long non-coding RNA produced by RNA polymerase V determines boundaries of heterochromatin
por: Böhmdorfer, Gudrun, et al.
Publicado: (2016)

The dynamic assembly of distinct RNA polymerase I complexes modulates rDNA transcription
por: Torreira, Eva, et al.
Publicado: (2017)

The nucleosomal barrier to promoter escape by RNA polymerase II is overcome by the chromatin remodeler Chd1
por: Skene, Peter J, et al.
Publicado: (2014)

Condensin controls recruitment of RNA polymerase II to achieve nematode X-chromosome dosage compensation
por: Kruesi, William S, et al.
Publicado: (2013)

HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells
por: Reeder, Jonathan E, et al.
Publicado: (2015)

CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo
por: Gu, Bo, et al.
Publicado: (2013)

Vernalization-triggered expression of the antisense transcript COOLAIR is mediated by CBF genes
por: Jeon, Myeongjune, et al.
Publicado: (2023)

Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi–Goutières syndrome
por: Lim, Yoong Wearn, et al.
Publicado: (2015)

RNA polymerase II CTD is dispensable for transcription and required for termination in human cells
por: Yahia, Yousra, et al.
Publicado: (2023)

Co-transcriptional R-loops are the main cause of estrogen-induced DNA damage
por: Stork, Caroline Townsend, et al.
Publicado: (2016)

Metagenomic chromosome conformation capture (meta3C) unveils the diversity of chromosome organization in microorganisms
por: Marbouty, Martial, et al.
Publicado: (2014)

Genetic dissection of the RNA polymerase II transcription cycle
por: Chou, Shao-Pei, et al.
Publicado: (2022)

Requirements for RNA polymerase II preinitiation complex formation in vivo
por: Petrenko, Natalia, et al.
Publicado: (2019)

Comparison of transcriptional initiation by RNA polymerase II across eukaryotic species
por: Petrenko, Natalia, et al.
Publicado: (2021)

Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery
por: Tonzi, Peter, et al.
Publicado: (2018)

RNA Polymerase II transcription independent of TBP in murine embryonic stem cells
por: Kwan, James ZJ, et al.
Publicado: (2023)

Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism
por: Scholl, Ute I, et al.
Publicado: (2015)

Rpb4/7 facilitates RNA polymerase II CTD dephosphorylation
por: Allepuz-Fuster, Paula, et al.
Publicado: (2014)

A stable mode of bookmarking by TBP recruits RNA polymerase II to mitotic chromosomes
por: Teves, Sheila S, et al.
Publicado: (2018)

RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit
por: Milligan, Laura, et al.
Publicado: (2017)

Reporter-ChIP-nexus reveals strong contribution of the Drosophila initiator sequence to RNA polymerase pausing
por: Shao, Wanqing, et al.
Publicado: (2019)

Brd4 activates P-TEFb for RNA polymerase II CTD phosphorylation
por: Itzen, Friederike, et al.
Publicado: (2014)

Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction
por: Ranjan, Anand, et al.
Publicado: (2020)

Mitotically heritable, RNA polymerase II-independent H3K4 dimethylation stimulates INO1 transcriptional memory
por: Sump, Bethany, et al.
Publicado: (2022)

Specific threonine-4 phosphorylation and function of RNA polymerase II CTD during M phase progression
por: Hintermair, Corinna, et al.
Publicado: (2016)

The starvation hormone, fibroblast growth factor-21, extends lifespan in mice
por: Zhang, Yuan, et al.
Publicado: (2012)

DNA deaminases induce break-associated mutation showers with implication of APOBEC3B and 3A in breast cancer kataegis
por: Taylor, Benjamin JM, et al.
Publicado: (2013)

Bidding the CpG island goodbye
por: Greally, John M
Publicado: (2013)

Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates
por: Long, Hannah K, et al.
Publicado: (2013)

Plants regenerated from tissue culture contain stable epigenome changes in rice
por: Stroud, Hume, et al.
Publicado: (2013)

A component of the mir-17-92 polycistronic oncomir promotes oncogene-dependent apoptosis
por: Olive, Virginie, et al.
Publicado: (2013)

When 19 is greater than 92
por: Zeitels, Lauren R, et al.
Publicado: (2013)

The budding yeast Centromere DNA Element II wraps a stable Cse4 hemisome in either orientation in vivo
por: Henikoff, Steven, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_pipu0sflog2dif056bf4qban9p