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New pathobiochemical insights into dystrophinopathy from the proteomics of senescent mdx mouse muscle

Primary abnormalities in the dystrophin gene cause X-linked muscular dystrophy, a highly progressive muscle wasting disorder of childhood. A spontaneous animal model of Duchenne muscular dystrophy is the mdx mouse, which presents a highly interesting phenotype that exhibits considerable variations i...

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Detalles Bibliográficos
Autores principales: Holland, Ashling, Dowling, Paul, Ohlendieck, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042888/
https://www.ncbi.nlm.nih.gov/pubmed/24917816
http://dx.doi.org/10.3389/fnagi.2014.00109