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Targeting central melanocortin receptors: a promising novel approach for treating alcohol abuse disorders

The melanocortin (MC) peptides are produced centrally by propiomelanocortin (POMC) neurons within the arcuate nucleus of the hypothalamus and act through five seven-transmembrane G-protein coupled melanocortin receptor (MCR) subtypes. The MC3R and MC4R subtypes, the most abundant central MCRs, are w...

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Detalles Bibliográficos
Autores principales: Olney, Jeffrey J., Navarro, Montserrat, Thiele, Todd E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4042890/
https://www.ncbi.nlm.nih.gov/pubmed/24917782
http://dx.doi.org/10.3389/fnins.2014.00128

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