Cargando…

Understanding the polypharmacological anticancer effects of Xiao Chai Hu Tang via a computational pharmacological model

Xiao Chai Hu Tang (XCHT), a traditional herbal formula, is widely administered as a cancer treatment. However, the underlying molecular mechanisms of its anticancer effects are not fully understood. In the present study, a computational pharmacological model that combined chemical space mapping, mol...

Descripción completa

Detalles Bibliográficos
Autores principales:	ZHENG, CHUN-SONG, WU, YIN-SHENG, BAO, HONG-JUAN, XU, XIAO-JIE, CHEN, XING-QIANG, YE, HONG-ZHI, WU, GUANG-WEN, XU, HUI-FENG, LI, XI-HAI, CHEN, JIA-SHOU, LIU, XIAN-XIANG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043560/ https://www.ncbi.nlm.nih.gov/pubmed/24926384 http://dx.doi.org/10.3892/etm.2014.1660

Ejemplares similares

Current Understanding on Antihepatocarcinoma Effects of Xiao Chai Hu Tang and Its Constituents
por: Zheng, Ningning, et al.
Publicado: (2013)

Network pharmacology and molecular docking study on the mechanism of colorectal cancer treatment using Xiao-Chai-Hu-Tang
por: Jin, Jingyun, et al.
Publicado: (2021)

Renal Protective Effect of Xiao-Chai-Hu-Tang on Diabetic Nephropathy of Type 1-Diabetic Mice
por: Lin, Chun-Ching, et al.
Publicado: (2012)

Xiao Chai Hu Tang for Peptic Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
por: Li, Min, et al.
Publicado: (2021)

THE HERBAL MIXTURE XIAO-CHAI-HU TANG (XCHT) INDUCES APOPTOSIS OF HUMAN HEPATOCELLULAR CARCINOMA HUH7 CELLS IN VITRO AND IN VIVO
por: Zhao, Jinyan, et al.
Publicado: (2017)

Inhibition by Xiao‐chai‐hu‐tang (TJ‐9) of Development of Hepatic Foci Induced by N‐Nitrosomorpholine in Sprague‐Dawley Rats
por: Tatsuta, Masaharu, et al.
Publicado: (1991)

Xiao-Chai-Hu Decoction Ameliorates Poly (I:C)-Induced Viral Pneumonia through Inhibiting Inflammatory Response and Modulating Serum Metabolism
por: Chen, Feng, et al.
Publicado: (2022)

Herbal Medicine (Sihogayonggolmoryeo-Tang or Chai-Hu-Jia-Long-Gu-Mu-Li-Tang) for Treating Hypertension:A Systematic Review and Meta-Analysis
por: Lee, Boram, et al.
Publicado: (2020)

Da-Chai-Hu-Tang Protects From Acute Intrahepatic Cholestasis by Inhibiting Hepatic Inflammation and Bile Accumulation via Activation of PPARα
por: Xu, Shihao, et al.
Publicado: (2022)

Efficacy and safety of Sihogayonggolmoryeo-tang (Saikokaryukotsuboreito, Chai-Hu-Jia-Long-Gu-Mu-Li-Tang) for post-stroke depression: A systematic review and meta-analysis
por: Kwon, Chan-Young, et al.
Publicado: (2019)

The Chinese medicine Chai Hu Li Zhong Tang protects against non-alcoholic fatty liver disease by activating AMPKα
por: Zhang, Meng, et al.
Publicado: (2018)

Herbal medicine Sihogayonggolmoryeo-tang or Chai-Hu-Jia-Long-Gu-Mu-Li-Tang for the treatment of post-stroke depression: A protocol for a systematic review and meta-analysis
por: Kwon, Chan-Young, et al.
Publicado: (2018)

Effects of Sihogayonggolmoryeo-tang (Saikokaryukotsuboreito or Chai-Hu-Jia-Long-Gu-Mu-Li-Tang) for insomnia disorder with prehypertension or stage 1 hypertension: A study protocol for a randomized controlled trial
por: Lee, Boram, et al.
Publicado: (2020)

Integrated Analysis of the Mechanisms of Da-Chai-Hu Decoction in Type 2 Diabetes Mellitus by a Network Pharmacology Approach
por: Ren, Beida, et al.
Publicado: (2020)

Computational Network Pharmacology–Based Strategy to Capture Key Functional Components and Decode the Mechanism of Chai-Hu-Shu-Gan-San in Treating Depression
por: Wang, Kexin, et al.
Publicado: (2021)

Treatment of depression with Chai Hu Shu Gan San: a systematic review and meta-analysis of 42 randomized controlled trials
por: Sun, Yan, et al.
Publicado: (2018)

Efficacy and Safety of Da-Chai-Hu-Tang in Lipid Profiles in High-Risk, Statin-Treated Patients with Residual HyperTG: A 12-Week, Randomized, Active-Control, Open Clinical Study
por: Lee, Young-Shin, et al.
Publicado: (2022)

Chai Jing: The Power of Vulnerability
por: Zhang, Jie
Publicado: (2019)

Targeted bile acid profiles reveal the liver injury amelioration of Da-Chai-Hu decoction against ANIT- and BDL-induced cholestasis
por: Zhou, YueHua, et al.
Publicado: (2022)

Concentration and detection of SARS coronavirus in sewage from Xiao Tang Shan Hospital and the 309th Hospital
por: Wang, Xin-Wei, et al.
Publicado: (2005)

Therapeutic Effects of Saireito (Chai-Ling-Tang), a Traditional Japanese Herbal Medicine, on Lymphedema Caused by Radiotherapy: A Case Series Study
por: Nagai, Aiko, et al.
Publicado: (2013)

The Polypharmacological Effects of Cannabidiol
por: Castillo-Arellano, Jorge, et al.
Publicado: (2023)

Advances in Computational Polypharmacology
por: Feldmann, Christian, et al.
Publicado: (2022)

Anticancer Action of Xiaoxianxiong Tang in Non-Small Cell Lung Cancer by Pharmacological Analysis and Experimental Validation
por: Ding, Rongzhen, et al.
Publicado: (2021)

Isolation and characterization of nanometre aggregates from a Bai-Hu-Tang decoction and their antipyretic effect
por: Lü, Shaowa, et al.
Publicado: (2018)

Xiao-Qing-Long-Tang shows preventive effect of asthma in an allergic asthma mouse model through neurotrophin regulation
por: Chang, Ren-Shiu, et al.
Publicado: (2013)

Real-World Study on Chai-Shi-Jie-Du Granules for the Treatment of Dengue Fever and the Possible Mechanisms Based on Network Pharmacology
por: Yang, Huiqin, et al.
Publicado: (2023)

The therapeutic effects and mechanisms of Long Chai Fang on chronic hepatitis B
por: Xu, Tingting, et al.
Publicado: (2021)

Jiang Tang Xiao Ke Granule, a Classic Chinese Herbal Formula, Improves the Effect of Metformin on Lipid and Glucose Metabolism in Diabetic Mice
por: Zhang, Yi, et al.
Publicado: (2016)

Polypharmacology of ambroxol in the treatment of COVID-19
por: Wang, Ziyuan, et al.
Publicado: (2023)

Computational polypharmacology comes of age
por: Rastelli, Giulio, et al.
Publicado: (2015)

Structural and Functional View of Polypharmacology
por: Moya-García, Aurelio, et al.
Publicado: (2017)

Network pharmacology evaluation of the active ingredients and potential targets of XiaoLuoWan for application to uterine fibroids
por: Yu, Yonghui, et al.
Publicado: (2020)

Da-Chai-Hu Decoction Ameliorates High Fat Diet-Induced Nonalcoholic Fatty Liver Disease Through Remodeling the Gut Microbiota and Modulating the Serum Metabolism
por: Cui, Huantian, et al.
Publicado: (2020)

Xiao-Qing-Long Tang Prevents Cardiomyocyte Hypertrophy, Fibrosis, and the Development of Heart Failure with Preserved Ejection Faction in Rats by Modulating the Composition of the Gut Microbiota
por: Zhou, Guo-Feng, et al.
Publicado: (2019)

Antidiabetic and Antioxidative Effect of Jiang Tang Xiao Ke Granule in High-Fat Diet and Low-Dose Streptozotocin Induced Diabetic Rats
por: Zhao, Dan-Dan, et al.
Publicado: (2014)

Network Pharmacology-Based Analysis of Xiao-Xu-Ming Decoction on the Treatment of Alzheimer’s Disease
por: Shen, Yanjia, et al.
Publicado: (2020)

Elucidating Polypharmacological Mechanisms of Polyphenols by Gene Module Profile Analysis
por: Li, Bin, et al.
Publicado: (2014)

Polypharmacological Cell-Penetrating Peptides from Venomous Marine Animals Based on Immunomodulating, Antimicrobial, and Anticancer Properties
por: Hemmati, Shiva, et al.
Publicado: (2022)

Automated design of ligands to polypharmacological profiles
por: Besnard, Jérémy, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_u6gmih08p76lb3u8akb8nk1iso