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Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two-dimensional tissue motion annular displacement
The early detection of abnormal left ventricular systolic functions in patients with hypertrophic cardiomyopathy (HCM) remains a challenge. The aim of this study was to identify a novel method for the assessment of left ventricular systolic function in patients with HCM. A total of 65 patients with...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043569/ https://www.ncbi.nlm.nih.gov/pubmed/24926326 http://dx.doi.org/10.3892/etm.2014.1617 |
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author | LIU, LIWEN TUO, SHENGJUN ZHANG, JIANLEI ZUO, LEI LIU, FANG HAO, LILI SUN, YANDAN YANG, LIPING SHAO, HONG QI, WEI ZHOU, XIAODONG GE, SHUPING |
author_facet | LIU, LIWEN TUO, SHENGJUN ZHANG, JIANLEI ZUO, LEI LIU, FANG HAO, LILI SUN, YANDAN YANG, LIPING SHAO, HONG QI, WEI ZHOU, XIAODONG GE, SHUPING |
author_sort | LIU, LIWEN |
collection | PubMed |
description | The early detection of abnormal left ventricular systolic functions in patients with hypertrophic cardiomyopathy (HCM) remains a challenge. The aim of this study was to identify a novel method for the assessment of left ventricular systolic function in patients with HCM. A total of 65 patients with HCM were included in this study. The patients were divided into obstructive HCM (HOCM; 16 cases) and non-obstructive HCM (NOHCM; 49 cases) groups. The healthy control group comprised 48 participants. Two-dimensional (2D) speckle-tracking technology was used to measure the left ventricular global and segmental longitudinal strains and mitral annular displacement (MADs). Compared with healthy control group, the six segmental strains and the global strain of the left ventricle (LS(global)) increased while six segmental MADs and MAD(global) of the mitral annulus decreased in the HOCM and NOHCM groups (P<0.05). In addition, the six segmental MADs of the mitral annulus were significantly negatively correlated with the six segmental strains of the left ventricle (r=−0.744 to −0.647, P<0.001). MAD(global) was significantly negatively correlated with LS(global) (r=−0.857, P<0.001). The tissue motion annular displacement (TMAD) at the midpoint was significantly negatively correlated with LS(global) (r=−0.871, P<0.001). The 2D TMAD technique of measuring MAD was feasible and practically approachable for rapidly evaluating the left ventricular longitudinal global and segmental systolic functions of patients with HCM. |
format | Online Article Text |
id | pubmed-4043569 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-40435692014-06-12 Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two-dimensional tissue motion annular displacement LIU, LIWEN TUO, SHENGJUN ZHANG, JIANLEI ZUO, LEI LIU, FANG HAO, LILI SUN, YANDAN YANG, LIPING SHAO, HONG QI, WEI ZHOU, XIAODONG GE, SHUPING Exp Ther Med Articles The early detection of abnormal left ventricular systolic functions in patients with hypertrophic cardiomyopathy (HCM) remains a challenge. The aim of this study was to identify a novel method for the assessment of left ventricular systolic function in patients with HCM. A total of 65 patients with HCM were included in this study. The patients were divided into obstructive HCM (HOCM; 16 cases) and non-obstructive HCM (NOHCM; 49 cases) groups. The healthy control group comprised 48 participants. Two-dimensional (2D) speckle-tracking technology was used to measure the left ventricular global and segmental longitudinal strains and mitral annular displacement (MADs). Compared with healthy control group, the six segmental strains and the global strain of the left ventricle (LS(global)) increased while six segmental MADs and MAD(global) of the mitral annulus decreased in the HOCM and NOHCM groups (P<0.05). In addition, the six segmental MADs of the mitral annulus were significantly negatively correlated with the six segmental strains of the left ventricle (r=−0.744 to −0.647, P<0.001). MAD(global) was significantly negatively correlated with LS(global) (r=−0.857, P<0.001). The tissue motion annular displacement (TMAD) at the midpoint was significantly negatively correlated with LS(global) (r=−0.871, P<0.001). The 2D TMAD technique of measuring MAD was feasible and practically approachable for rapidly evaluating the left ventricular longitudinal global and segmental systolic functions of patients with HCM. D.A. Spandidos 2014-06 2014-03-12 /pmc/articles/PMC4043569/ /pubmed/24926326 http://dx.doi.org/10.3892/etm.2014.1617 Text en Copyright © 2014, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Articles LIU, LIWEN TUO, SHENGJUN ZHANG, JIANLEI ZUO, LEI LIU, FANG HAO, LILI SUN, YANDAN YANG, LIPING SHAO, HONG QI, WEI ZHOU, XIAODONG GE, SHUPING Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two-dimensional tissue motion annular displacement |
title | Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two-dimensional tissue motion annular displacement |
title_full | Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two-dimensional tissue motion annular displacement |
title_fullStr | Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two-dimensional tissue motion annular displacement |
title_full_unstemmed | Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two-dimensional tissue motion annular displacement |
title_short | Reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: Study of two-dimensional tissue motion annular displacement |
title_sort | reduction of left ventricular longitudinal global and segmental systolic functions in patients with hypertrophic cardiomyopathy: study of two-dimensional tissue motion annular displacement |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043569/ https://www.ncbi.nlm.nih.gov/pubmed/24926326 http://dx.doi.org/10.3892/etm.2014.1617 |
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