Downregulation of Connexin 43 promotes vascular cell loss and excess permeability associated with the development of vascular lesions in the diabetic retina

PURPOSE: To determine whether downregulation of Connexin 43 (Cx43) expression promotes development of acellular capillaries (ACs), pericyte loss (PL), excess permeability, and retinal thickening in rat retinas. METHODS: Control rats, diabetic rats, and rats intravitreally injected with Cx43 siRNA or...

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Detalles Bibliográficos
Autores principales: Tien, Thomas, Muto, Tetsuya, Barrette, Kevin, Challyandra, Lucky, Roy, Sayon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043608/
https://www.ncbi.nlm.nih.gov/pubmed/24940027

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