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Prior EGFR tyrosine-kinase inhibitor therapy did not influence the efficacy of subsequent pemetrexed plus platinum in advanced chemonaïve patients with EGFR-mutant lung adenocarcinoma

BACKGROUND: Tumor cells before and after epidermal growth-factor receptor (EGFR) tyrosine-kinase inhibitor (TKI) therapy might display different characteristics. The aim of this study was to evaluate the influence of prior EGFR TKI therapy on the efficacy of subsequent pemetrexed plus platinum (PP)...

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Detalles Bibliográficos
Autores principales: Tseng, Jeng-Sen, Yang, Tsung-Ying, Chen, Kun-Chieh, Hsu, Kuo-Hsuan, Yu, Chong-Jen, Liao, Wei-Yu, Tsai, Chi-Ren, Tsai, Meen-Hsin, Yu, Sung-Liang, Su, Kang-Yi, Chen, Jeremy JW, Chen, Hsuan-Yu, Chang, Gee-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043805/
https://www.ncbi.nlm.nih.gov/pubmed/24920920
http://dx.doi.org/10.2147/OTT.S62639