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Prior EGFR tyrosine-kinase inhibitor therapy did not influence the efficacy of subsequent pemetrexed plus platinum in advanced chemonaïve patients with EGFR-mutant lung adenocarcinoma
BACKGROUND: Tumor cells before and after epidermal growth-factor receptor (EGFR) tyrosine-kinase inhibitor (TKI) therapy might display different characteristics. The aim of this study was to evaluate the influence of prior EGFR TKI therapy on the efficacy of subsequent pemetrexed plus platinum (PP)...
Autores principales: | Tseng, Jeng-Sen, Yang, Tsung-Ying, Chen, Kun-Chieh, Hsu, Kuo-Hsuan, Yu, Chong-Jen, Liao, Wei-Yu, Tsai, Chi-Ren, Tsai, Meen-Hsin, Yu, Sung-Liang, Su, Kang-Yi, Chen, Jeremy JW, Chen, Hsuan-Yu, Chang, Gee-Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043805/ https://www.ncbi.nlm.nih.gov/pubmed/24920920 http://dx.doi.org/10.2147/OTT.S62639 |
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