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Positron emission tomographic monitoring of dual phosphatidylinositol-3-kinase and mTOR inhibition in anaplastic large cell lymphoma
BACKGROUND: Dual phosphatidylinositol-3-kinase (PI3K)/mammalian target of rapamycin (mTOR) inhibition offers an attractive therapeutic strategy in anaplastic large cell lymphoma depending on oncogenic nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) signaling. We tested the efficacy of a novel dua...
Autores principales: | Graf, Nicolas, Li, Zhoulei, Herrmann, Ken, Weh, Daniel, Aichler, Michaela, Slawska, Jolanta, Walch, Axel, Peschel, Christian, Schwaiger, Markus, Buck, Andreas K, Dechow, Tobias, Keller, Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043809/ https://www.ncbi.nlm.nih.gov/pubmed/24920919 http://dx.doi.org/10.2147/OTT.S59314 |
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