Down-Regulation of mir-221 and mir-222 Restrain Prostate Cancer Cell Proliferation and Migration That Is Partly Mediated by Activation of SIRT1

Studies have shown that miR-221 and miR-222 are deregulated in many cancers, including prostate cancer. Nevertheless, the biological role and the underlying mechanisms of miR-221 and miR-222 in the pathogenesis of androgen-independent prostate cancer are still not clear. The proliferation, apoptosis...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Yang, Yingmei, Gan, Rong, Zhao, Lingxu, Li, Wei, Zhou, Huaibin, Wang, Xiaojuan, Lu, Jianxin, Meng, Qing H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043919/
https://www.ncbi.nlm.nih.gov/pubmed/24892674
http://dx.doi.org/10.1371/journal.pone.0098833

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