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Preparation and Characterization of a Novel Aspirin Derivative with Anti-Thrombotic and Gastric Mucosal Protection Properties

The use of acetylsalicylic acid (ASP) is limited by its adverse effects, especially the effect on the gastric mucosa. To address this problem, we synthesized a derivative form of ASP, prepared by modification of ASP with nano-hydroxyapatite (a kind of inorganic particle containing Ca(2+)). The deriv...

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Detalles Bibliográficos
Autores principales: Zhen, Xi-E, Zong, Ming, Gao, Sai-Nan, Cao, Yong-Gang, Jiang, Lei, Chen, Shu-Xin, Wang, Kuan, Sun, Shi-Qin, Peng, Hai-Sheng, Bai, Yu-Hua, Li, Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4043976/
https://www.ncbi.nlm.nih.gov/pubmed/24892779
http://dx.doi.org/10.1371/journal.pone.0098513