Silencing of KIF14 interferes with cell cycle progression and cytokinesis by blocking the p27(Kip1) ubiquitination pathway in hepatocellular carcinoma

Although it has been suggested that kinesin family member 14 (KIF14) has oncogenic potential in various cancers, including hepatocellular carcinoma (HCC), the molecular mechanism of this potential remains unknown. We aimed to elucidate the role of KIF14 in hepatocarcinogenesis by knocking down KIF14...

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Detalles Bibliográficos
Autores principales: Xu, Haidong, Choe, Chungyoul, Shin, Seung-Hun, Park, Sung-Won, Kim, Ho-Shik, Jung, Seung-Hyun, Yim, Seon-Hee, Kim, Tae-Min, Chung, Yeun-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4044675/
https://www.ncbi.nlm.nih.gov/pubmed/24854087
http://dx.doi.org/10.1038/emm.2014.23

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