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The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast

DNA interstrand cross-links (ICLs) represent a physical barrier to the progression of cellular machinery involved in DNA metabolism. Thus, this type of adduct represents a serious threat to genomic stability and as such, several DNA repair pathways have evolved in both higher and lower eukaryotes to...

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Detalles Bibliográficos
Autores principales: Fontebasso, Y., Etheridge, T.J., Oliver, A.W., Murray, J.M., Carr, A.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045212/
https://www.ncbi.nlm.nih.gov/pubmed/24192486
http://dx.doi.org/10.1016/j.dnarep.2013.10.003