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Exposure to excess insulin (glargine) induces type 2 diabetes mellitus in mice fed on a chow diet
We have previously shown that insulin plays an important role in the nutrient-induced insulin resistance. In this study, we tested the hypothesis that chronic exposure to excess long-acting insulin (glargine) can cause typical type 2 diabetes mellitus (T2DM) in normal mice fed on a chow diet. C57BL/...
Autores principales: | Yang, Xuefeng, Mei, Shuang, Gu, Haihua, Guo, Huailan, Zha, Longying, Cai, Junwei, Li, Xuefeng, Liu, Zhenqi, Cao, Wenhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045231/ https://www.ncbi.nlm.nih.gov/pubmed/24741073 http://dx.doi.org/10.1530/JOE-14-0117 |
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