Structural studies of the spliceosome: zooming into the heart of the machine()

Spliceosomes are large, dynamic ribonucleoprotein complexes that catalyse the removal of introns from messenger RNA precursors via a two-step splicing reaction. The recent crystal structure of Prp8 has revealed Reverse Transcriptase-like, Linker and Endonuclease-like domains. The intron branch-point...

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Detalles Bibliográficos
Autores principales: Galej, Wojciech P, Nguyen, Thi Hoang Duong, Newman, Andrew J, Nagai, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045393/
https://www.ncbi.nlm.nih.gov/pubmed/24480332
http://dx.doi.org/10.1016/j.sbi.2013.12.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045393/
https://www.ncbi.nlm.nih.gov/pubmed/24480332
http://dx.doi.org/10.1016/j.sbi.2013.12.002

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