Cargando…
Hyaluronan Is Not a Ligand but a Regulator of Toll-Like Receptor Signaling in Mesangial Cells: Role of Extracellular Matrix in Innate Immunity
Glomerular mesangial cells (MC), like most cell types secrete hyaluronan (HA), which attached to the cell surface via CD44, is the backbone of a hydrophilic gel matrix around these cells. Reduced extracellular matrix thickness and viscosity result from HA cleavage during inflammation. HA fragments w...
Autores principales: | Ebid, Rainer, Lichtnekert, Julia, Anders, Hans-Joachim |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045461/ https://www.ncbi.nlm.nih.gov/pubmed/24967246 http://dx.doi.org/10.1155/2014/714081 |
Ejemplares similares
-
Activation of Innate Immunity by Bacterial Ligands of Toll-Like Receptors
por: Akhmatova, Nelli K., et al.
Publicado: (2014) -
Innate immunity and Toll-like receptors
por: O'Neill, LAJ
Publicado: (2004) -
Neonatal innate immunity and Toll-like receptor
por: Yoon, Hye Sun
Publicado: (2010) -
Toll-Like Receptors in Antiviral Innate Immunity
por: Lester, Sandra N., et al.
Publicado: (2014) -
Innate Immune Regulation by Toll-Like Receptors in the Brain
por: Mallard, Carina
Publicado: (2012)