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Hepatitis E Virus Serosurvey among Pet Dogs and Cats in Several Developed Cities in China

Infection by Hepatitis E virus (HEV), as a zoonotic disease virus, is well studied in pigs in China, but few studies in pets have been performed. This study was designed to characterize the prevalence of HEV infection among pet dogs and cats in major metropolitan areas of China. We conducted a seroe...

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Autores principales: Liang, Huanbin, Chen, Jidang, Xie, Jiexiong, Sun, Long, Ji, Fangxiao, He, Shuyi, Zheng, Yun, Liang, Chumin, Zhang, Guihong, Su, Shuo, Li, Shoujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045666/
https://www.ncbi.nlm.nih.gov/pubmed/24896257
http://dx.doi.org/10.1371/journal.pone.0098068
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author Liang, Huanbin
Chen, Jidang
Xie, Jiexiong
Sun, Long
Ji, Fangxiao
He, Shuyi
Zheng, Yun
Liang, Chumin
Zhang, Guihong
Su, Shuo
Li, Shoujun
author_facet Liang, Huanbin
Chen, Jidang
Xie, Jiexiong
Sun, Long
Ji, Fangxiao
He, Shuyi
Zheng, Yun
Liang, Chumin
Zhang, Guihong
Su, Shuo
Li, Shoujun
author_sort Liang, Huanbin
collection PubMed
description Infection by Hepatitis E virus (HEV), as a zoonotic disease virus, is well studied in pigs in China, but few studies in pets have been performed. This study was designed to characterize the prevalence of HEV infection among pet dogs and cats in major metropolitan areas of China. We conducted a seroepidemiological survey from 2012 to 2013 in 5 developed cities, Beijing, Shanghai, Canton, Shenzhen and Macao, by enzyme-linked immunosorbent assay (ELISA). The overall HEV seroprevalence in 658 dog and 191 cat serum samples was 21.12% and 6.28%, respectively. The analysis in dogs suggested that there were significant differences among cities, and the positive rate of HEV-specific antibody in all cities ranged from 6.06% (Shenzhen) to 29.34% (Beijing). Older pet cats have a high risk (OR, 10.25) for HEV seropositivity, but no strong relationship was observed between different genders and age groups. Additionally, it was revealed that stray dogs, omnivorous pet dogs and pet cats who share food, such as kitchen residue, with the general population would have a higher risk for HEV seropositivity. The odds ratios for these groups are 2.40, 2.83 and 5.39, respectively, compared with pet dogs and cats fed on commercial food. In this study, we first report that HEV is prevalent in pet dogs and cats in several large cities in China. Swill and kitchen residue may be a potential risk for HEV transmission from human to pets. As the sample size was relatively small in this study and may not be fully representative of China, further investigation is required to confirm the conclusions.
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spelling pubmed-40456662014-06-09 Hepatitis E Virus Serosurvey among Pet Dogs and Cats in Several Developed Cities in China Liang, Huanbin Chen, Jidang Xie, Jiexiong Sun, Long Ji, Fangxiao He, Shuyi Zheng, Yun Liang, Chumin Zhang, Guihong Su, Shuo Li, Shoujun PLoS One Research Article Infection by Hepatitis E virus (HEV), as a zoonotic disease virus, is well studied in pigs in China, but few studies in pets have been performed. This study was designed to characterize the prevalence of HEV infection among pet dogs and cats in major metropolitan areas of China. We conducted a seroepidemiological survey from 2012 to 2013 in 5 developed cities, Beijing, Shanghai, Canton, Shenzhen and Macao, by enzyme-linked immunosorbent assay (ELISA). The overall HEV seroprevalence in 658 dog and 191 cat serum samples was 21.12% and 6.28%, respectively. The analysis in dogs suggested that there were significant differences among cities, and the positive rate of HEV-specific antibody in all cities ranged from 6.06% (Shenzhen) to 29.34% (Beijing). Older pet cats have a high risk (OR, 10.25) for HEV seropositivity, but no strong relationship was observed between different genders and age groups. Additionally, it was revealed that stray dogs, omnivorous pet dogs and pet cats who share food, such as kitchen residue, with the general population would have a higher risk for HEV seropositivity. The odds ratios for these groups are 2.40, 2.83 and 5.39, respectively, compared with pet dogs and cats fed on commercial food. In this study, we first report that HEV is prevalent in pet dogs and cats in several large cities in China. Swill and kitchen residue may be a potential risk for HEV transmission from human to pets. As the sample size was relatively small in this study and may not be fully representative of China, further investigation is required to confirm the conclusions. Public Library of Science 2014-06-04 /pmc/articles/PMC4045666/ /pubmed/24896257 http://dx.doi.org/10.1371/journal.pone.0098068 Text en © 2014 Liang et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Liang, Huanbin
Chen, Jidang
Xie, Jiexiong
Sun, Long
Ji, Fangxiao
He, Shuyi
Zheng, Yun
Liang, Chumin
Zhang, Guihong
Su, Shuo
Li, Shoujun
Hepatitis E Virus Serosurvey among Pet Dogs and Cats in Several Developed Cities in China
title Hepatitis E Virus Serosurvey among Pet Dogs and Cats in Several Developed Cities in China
title_full Hepatitis E Virus Serosurvey among Pet Dogs and Cats in Several Developed Cities in China
title_fullStr Hepatitis E Virus Serosurvey among Pet Dogs and Cats in Several Developed Cities in China
title_full_unstemmed Hepatitis E Virus Serosurvey among Pet Dogs and Cats in Several Developed Cities in China
title_short Hepatitis E Virus Serosurvey among Pet Dogs and Cats in Several Developed Cities in China
title_sort hepatitis e virus serosurvey among pet dogs and cats in several developed cities in china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045666/
https://www.ncbi.nlm.nih.gov/pubmed/24896257
http://dx.doi.org/10.1371/journal.pone.0098068
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