CXCR7 Controls Competition for Recruitment of β-Arrestin 2 in Cells Expressing Both CXCR4 and CXCR7

Chemokine CXCL12 promotes growth and metastasis of more than 20 different human cancers, as well as pathogenesis of other common diseases. CXCL12 binds two different receptors, CXCR4 and CXCR7, both of which recruit and signal through the cytosolic adapter protein β-arrestin 2. Differences in CXCL12...

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Detalles Bibliográficos
Autores principales: Coggins, Nathaniel L., Trakimas, Danielle, Chang, S. Laura, Ehrlich, Anna, Ray, Paramita, Luker, Kathryn E., Linderman, Jennifer J., Luker, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045718/
https://www.ncbi.nlm.nih.gov/pubmed/24896823
http://dx.doi.org/10.1371/journal.pone.0098328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045718/
https://www.ncbi.nlm.nih.gov/pubmed/24896823
http://dx.doi.org/10.1371/journal.pone.0098328

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