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CXCR7 Controls Competition for Recruitment of β-Arrestin 2 in Cells Expressing Both CXCR4 and CXCR7
Chemokine CXCL12 promotes growth and metastasis of more than 20 different human cancers, as well as pathogenesis of other common diseases. CXCL12 binds two different receptors, CXCR4 and CXCR7, both of which recruit and signal through the cytosolic adapter protein β-arrestin 2. Differences in CXCL12...
Autores principales: | Coggins, Nathaniel L., Trakimas, Danielle, Chang, S. Laura, Ehrlich, Anna, Ray, Paramita, Luker, Kathryn E., Linderman, Jennifer J., Luker, Gary D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045718/ https://www.ncbi.nlm.nih.gov/pubmed/24896823 http://dx.doi.org/10.1371/journal.pone.0098328 |
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