Cargando…

Cyanidin 3-O-Glucoside Reduces Helicobacter pylori VacA-Induced Cell Death of Gastric KATO III Cells through Inhibition of the SecA Pathway

Two key virulence factors of Helicobacter pylori are the secreted virulent proteins of vacuolating toxin A (VacA) and cytotoxin associated protein A (CagA) which lead to damages of gastric epithelial cells. We previously identified that the cyanidin 3-O-glucoside (C3G) inhibits the secretion of both...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Sa-Hyun, Woo, Hyunjun, Park, Min, Rhee, Ki-Jong, Moon, Cheol, Lee, Dongsup, Seo, Woo Duck, Kim, Jong Bae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2014
Materias:	Short Research Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045794/ https://www.ncbi.nlm.nih.gov/pubmed/24904230 http://dx.doi.org/10.7150/ijms.7167

Ejemplares similares

Inhibitory Effects of Anthocyanins on Secretion of Helicobacter pylori CagA and VacA Toxins
por: Kim, Sa-Hyun, et al.
Publicado: (2012)

An Overview of Helicobacter pylori VacA Toxin Biology
por: Foegeding, Nora J., et al.
Publicado: (2016)

Diversification of the vacAs1m1 and vacAs2m2 Strains of Helicobacter pylori in Meriones unguiculatus
por: Mendoza-Elizalde, Sandra, et al.
Publicado: (2016)

Immunosuppressive and Proinflammatory Activities of the VacA Toxin of Helicobacter pylori
por: Montecucco, Cesare, et al.
Publicado: (2003)

Sphingomyelin Functions as a Novel Receptor for Helicobacter pylori VacA
por: Gupta, Vijay R., et al.
Publicado: (2008)

Prevalence of Helicobacter pylori vacA different genotypes in Isfahan, Iran
por: Havaei, S. Asghar, et al.
Publicado: (2014)

Expression and Antigenic Evaluation of VacA Antigenic Fragment of Helicobacter Pylori
por: Hasanzadeh, Leila, et al.
Publicado: (2013)

Endoplasmic Reticulum Stress Contributes to Helicobacter Pylori VacA-Induced Apoptosis
por: Akazawa, Yuko, et al.
Publicado: (2013)

Helicobacter pylori cagA and vacA genes in dyspeptic Ghanaian patients
por: Archampong, Timothy N., et al.
Publicado: (2017)

Treatment with Helicobacter pylori-derived VacA attenuates allergic airway disease
por: Reuter, Sebastian, et al.
Publicado: (2023)

Serum VEGF Levels in Helicobacter pylori Infection and Correlation with Helicobacter pylori cagA and vacA Genes
por: Siregar, Gontar, et al.
Publicado: (2017)

Helicobacter pylori vacA genotype is a predominant determinant of immune response to Helicobacter pylori CagA
por: Link, Alexander, et al.
Publicado: (2017)

Establishment of serine protease htrA mutants in Helicobacter pylori is associated with secA mutations
por: Zawilak-Pawlik, Anna, et al.
Publicado: (2019)

Remodeling the host environment: modulation of the gastric epithelium by the Helicobacter pylori vacuolating toxin (VacA)
por: Kim, Ik-Jung, et al.
Publicado: (2012)

Relevance of vacA Genotypes of Helicobacter pylori to cagA Status and Its Clinical Outcome
por: Park, Sill Moo, et al.
Publicado: (2001)

Selective Inhibition of Ii-dependent Antigen Presentation by Helicobacter pylori Toxin VacA
por: Molinari, Maurizio, et al.
Publicado: (1998)

The Versatility of the Helicobacter pylori Vacuolating Cytotoxin VacA in Signal Transduction and Molecular Crosstalk
por: Backert, Steffen, et al.
Publicado: (2010)

Vacuolating cytotoxin A (VacA), a key toxin for Helicobacter pylori pathogenesis
por: Palframan, Samuel L., et al.
Publicado: (2012)

VacA, the vacuolating cytotoxin of Helicobacter pylori, binds to multimerin 1 on human platelets
por: Satoh, Kaneo, et al.
Publicado: (2013)

vacA Genotype Status of Helicobacter pylori Isolated from Foods with Animal Origin
por: Saeidi, Elnaz, et al.
Publicado: (2016)

Helicobacter pylori targets mitochondrial import and components of mitochondrial DNA replication machinery through an alternative VacA-dependent and a VacA-independent mechanisms
por: Chatre, Laurent, et al.
Publicado: (2017)

DNA Sequence Analysis of South African Helicobacter pylori Vacuolating Cytotoxin Gene (vacA)
por: Tanih, Nicoline F., et al.
Publicado: (2011)

Characterization of virulence genes cagA and vacA in Helicobacter Pylori and their prevalence in gastrointestinal disorders
por: Cogo, Laura Lúcia, et al.
Publicado: (2011)

A Role for the Vacuolating Cytotoxin, VacA, in Colonization and Helicobacter pylori–Induced Metaplasia in the Stomach
por: Winter, Jody A., et al.
Publicado: (2014)

New genotypes of Helicobacter Pylori VacA d-region identified from global strains
por: Soyfoo, Djaleel Muhammad, et al.
Publicado: (2021)

Genotyping of Helicobacter pylori Virulence Genes cagA and vacA: Regional and National Study
por: Kishk, Rania M., et al.
Publicado: (2021)

Evaluating CagA and VacA Oncoproteins of Helicobacter pylori in Oral Potentially Malignant Disorders
por: Sekar, Ramya, et al.
Publicado: (2021)

Host cell sensing and restoration of mitochondrial function and metabolism within Helicobacter pylori VacA intoxicated cells
por: Seeger, Ami Y., et al.
Publicado: (2023)

The Structure of Clostridioides difficile SecA2 ATPase Exposes Regions Responsible for Differential Target Recognition of the SecA1 and SecA2-Dependent Systems
por: Lindič, Nataša, et al.
Publicado: (2020)

High Diversity of vacA and cagA Helicobacter pylori Genotypes in Patients with and without Gastric Cancer
por: López-Vidal, Yolanda, et al.
Publicado: (2008)

Acid-induced Dissociation of VacA, the Helicobacter pylori Vacuolating Cytotoxin, Reveals Its Pattern of Assembly
por: Cover, Timothy L., et al.
Publicado: (1997)

cagA and vacA in strains of Helicobacter pylori from ulcer and non-ulcerative dyspepsia patients
por: Faundez, Gustavo, et al.
Publicado: (2002)

Prevalence of Helicobacter pylori vacA, cagA and iceA genotypes and correlation with clinical outcome
por: WEI, GUO-CHAO, et al.
Publicado: (2012)

Association between Helicobacter pylori, cagA, and vacA Status and Clinical Presentation in Iranian Children
por: Rafeey, Mandana, et al.
Publicado: (2013)

Helicobacter pylori VacA toxin causes cell death by inducing accumulation of cytoplasmic connexin 43
por: Yahiro, K, et al.
Publicado: (2015)

A systematic review on the association between the Helicobacter pylori vacA i genotype and gastric disease
por: Liu, Xian, et al.
Publicado: (2016)

Helicobacter pylori vacA Genotypes in Chronic Gastritis and Gastric Carcinoma Patients from Macau, China
por: Pinto-Ribeiro, Ines, et al.
Publicado: (2016)

Helicobacter pylori vacA transcription is genetically-determined and stratifies the level of human gastric inflammation and atrophy
por: Sinnett, Charlotte G, et al.
Publicado: (2016)

Natural history of Helicobacter pylori VacA toxin in human gastric epithelium in vivo: vacuoles and beyond
por: Necchi, Vittorio, et al.
Publicado: (2017)

VacA promotes CagA accumulation in gastric epithelial cells during Helicobacter pylori infection
por: Abdullah, Majd, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_b6vogqgvvdfe84ntc2905dqbmp