Protective Role of Glutathione Peroxidase 4 in Laser-Induced Choroidal Neovascularization in Mice

PURPOSE: To evaluate the influence of glutathione peroxidase 4 (GPx4) expression in retinal pigment epithelium (RPE)/choroid tissue using a mouse model of laser-induced choroidal neovascularization (CNV). METHODS: In this study, GPx4(+/−), GPx4(+/+), and GPx4-overexpressing transgenic mice were crea...

Descripción completa

Detalles Bibliográficos
Autores principales: Roggia, Murilo Felix, Imai, Hirotaka, Shiraya, Tomoyasu, Noda, Yasuo, Ueta, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045803/
https://www.ncbi.nlm.nih.gov/pubmed/24897344
http://dx.doi.org/10.1371/journal.pone.0098864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045803/
https://www.ncbi.nlm.nih.gov/pubmed/24897344
http://dx.doi.org/10.1371/journal.pone.0098864

Ejemplares similares