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Plasma Interleukin-27 (IL-27) Levels Are Not Modulated in Patients with Chronic HIV-1 Infection

OBJECTIVE: IL-27 is an immunomodulatory cytokine with potent anti-HIV properties in PBMCs, CD4+ T cells, macrophages and immature dendritic cells. Previous smaller studies have suggested that HIV-1 infection may alter IL-27 and influence HIV-1 pathogenesis. The aim of this study was to examine the r...

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Detalles Bibliográficos
Autores principales: Swaminathan, Sanjay, Hu, Zonghui, Rupert, Adam W., Higgins, Jeanette M., Dewar, Robin L., Stevens, Randy, Chen, Qian, Rehm, Catherine A., Metcalf, Julia A., Baseler, Michael W., Lane, H. Clifford, Imamichi, Tomozumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045808/
https://www.ncbi.nlm.nih.gov/pubmed/24896094
http://dx.doi.org/10.1371/journal.pone.0098989