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SIRT6 Is Required for Normal Retinal Function

The retina is one of the major energy consuming tissues within the body. In this context, synaptic transmission between light-excited rod and cone photoreceptors and downstream ON-bipolar neurons is a highly demanding energy consuming process. Sirtuin 6 (SIRT6), a NAD-dependent deacylase, plays a ke...

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Detalles Bibliográficos
Autores principales: Silberman, Dafne M., Ross, Kenneth, Sande, Pablo H., Kubota, Shunsuke, Ramaswamy, Sridhar, Apte, Rajendra S., Mostoslavsky, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045872/
https://www.ncbi.nlm.nih.gov/pubmed/24896097
http://dx.doi.org/10.1371/journal.pone.0098831